Host and microbiome contributions to skin infections
Start Date
2017
Lead Organisation
Growing Up in New Zealand
Lead Researcher
Cameron Grant
Access Type
Internal
Primary Classification
Health and Wellbeing
Compared to other developed countries, New Zealand has one of the highest rates of serious skin infections; particularly among children. Childhood skin infection hospitalisation rates have doubled since 1990. The reasons for this and the mechanisms by which environmental exposures lead to increased rates of skin infection remain unknown. The study will describe rates of Staphylococcus Aureus and Streptococcus Pyogenes colonisation and skin infections at 5 years of age. Comparisons will be made between colonised and non-colonised children with and without infection to determine if there are (i) host genetic, and (ii) microbiome differences, associated with colonisation or infection.